Déborah BOURC’HIS is leading the Epigenetic Decisions and Reproduction group in the Department of Genetics and Developmental Biology at the Institut Curie, Paris, since 2009.
Her interests are related to the epigenetic control of mammalian reproduction, with a special focus on DNA methylation-regulated events. Her research touches upon several important aspects of mammalian biology such as genomic imprinting and transposon control. She obtained her PhD in 2000 from the University Paris 7 and was a post-doctoral fellow at Columbia University, New York from 2000 to 2005. Among her most important findings is the identification of the DNA methyltransferase cofactor DNMT3L as involved in the establishment of genomic methylation pattersn in the mammalin germline. She more recently focused her work on transient forms of imprinting, which relate to loci which maintain parent-specific DNA methylation patterns only for a few days after fertilization.